Pure risk: only two outcomes, loss or no loss. There is no chance of gain. Examples: an illness, a disabling injury, a hospital stay, a fire. Insurers cover pure risks.
Speculative risk: you might gain or you might lose. Examples: buying stock, opening a new business location, gambling. Insurers do not cover speculative risk, because insurance indemnifies losses; it does not back ventures taken on in hope of profit.